Serum levels of angiogenic cytokines in psoriatic arthritis and SAPHO syndrome

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Serum levels of angiogenic cytokines in psoriatic arthritis and SAPHO syndrome.

INTRODUCTION Angiogenesis is involved in the pathogenesis of arthritis. OBJECTIVES The aim of the study was to assess the serum levels of selected angiogenic cytokines and their association with clinical presentation in patients with psoriatic arthritis (PsA) and SAPHO syndrome. PATIENTS AND METHODS We studied 98 patients: 80 with PsA and 18 with SAPHO syndrome. The following data were reco...

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Serum IL-6 and IL-23 Levels and Their Correlation with Angiogenic Cytokines and Disease Activity in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome

OBJECTIVES To assess serum interleukin-6 (IL-6) and interleukin-23 (IL-23) and their correlation with angiogenic cytokines and disease activity in ankylosing spondylitis (AS), psoriatic arthritis (PsA), and SAPHO syndrome. PATIENTS AND METHODS We studied 152 spondyloarthritis (SpA) patients: 69 PsA, 61 AS, 22 SAPHO, and 29 controls. We recorded age, sex, disease duration, and treatment. We as...

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SAPHO syndrome or psoriatic arthritis? A familial case study.

OBJECTIVE To discuss the relationships between SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome and the group of spondylarthropathies. METHODS Few reports of familial SAPHO have been published. We describe three children, two sisters and one brother, whose clinical and radiological presentation was in accordance with SAPHO syndrome. RESULTS Two children developed psor...

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Serum uric acid levels in psoriatic arthritis.

Serum uric acid levels were determined in patients with psoriatic arthritis on and off medication, with rheumatoid arthritis on no medication likely to alter serum values, and in patients with uncomplicated psoriasis. Values in males were higher than those in females. A larger prevalence of values above the normal range were seen in males with psoriatic arthritis on uncontrolled medication (13-...

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Angiogenic and Inflammatory Properties of Psoriatic Arthritis

Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy associated with psoriasis and included in seronegative spondyloarthropathy. PsA has several unique characteristics different from rheumatoid arthritis (RA), such as enthesopathy, dactylitis, and abnormal bone remodeling. As compared with synovitis of RA (pannus), proliferation of PsA synovium is mild and characterized by hypervascu...

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ژورنال

عنوان ژورنال: Polish Archives of Internal Medicine

سال: 2013

ISSN: 1897-9483

DOI: 10.20452/pamw.1772